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    Hybrid Monoterpenoid Indole Alkaloids Obtained as Artifacts from Rauvolfia tetraphylla, Nat. Prod. Bioprospect., 2015, 5: 247–253.
    發布時間:2019-08-02 閱讀數:927 來源:原創
    分享到:

    Yuan Gao . Dong-Sheng Zhou . Ping Hai . Yan Li . Fei Wang


    Received: 2 September 2015 / Accepted: 24 September 2015 / Published online: 29 September 2015

    © The Author(s) 2015. This article is published with open access at Springerlink.com


    Abstract

    Five new hybrid monoterpenoid indole alkaloids bearing an unusual 2,2-dimethyl-4-oxopiperidin-6-yl moiety, namely rauvotetraphyllines F–H (1, 3, 4), 17-epi-rauvotetraphylline F (2) and 21-epi-rauvotetraphylline H (5), were isolated from the aerial parts of Rauvolfia tetraphylla. Their structures were established by extensive spectroscopic analysis. The new alkaloids were evaluated for their cytotoxicity in vitro against five human cancer cell lines.



    文章鏈接:https://link.springer.xilesou.top/article/10.1007/s13659-015-0074-2


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